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Lower Gastrointestinal Cancer

Enhanced Recovery After Surgery in Colorectal Surgery


Enhanced Recovery After Surgery (ERAS) pathways encompass an integrated approach to comprehensive surgical care throughout the preoperative, intraoperative, and postoperative phases to optimize patients for surgery, their care, and outcomes to achieve early postoperative recovery

16/01/2024

Management of Appendiceal Adenocarcinoma


Primary appendiceal malignancy is a rare diagnosis. It makes up approximately 0.8-1.4% of appendectomy specimens, and its incidence continues to hover around 0.12/1,000,000 person-years [1]. Despite their rarity, the burden of appendiceal tumors lies in their aggressive nature, with at least 74% of appendiceal cancer cases having spread at their initial diagnosis, 39% having developed regional metastases and 35% having developed distant metastases

21/11/2023

Management of Colorectal Cancer Liver Metastases


Colorectal cancer (CRC) is the third most commonly diagnosed cancer in men and women

17/05/2023

Radiation Therapy for Locally Advanced Rectal Cancer


Colorectal cancer is the second most common cancer diagnosed in women and the third most common in men, accounting for nearly 900,000 deaths worldwide each year

17/05/2023

Personalized Colorectal Cancer Management in Older Adults: Summary and Recommendations


A globally aging population has brought about an increasing number of older adults who require surgical intervention for a variety of ailments, including colorectal cancer. 

10/05/2023

Palliative Care for Colorectal Cancer


Colorectal cancer (CRC) is the third most common cancer diagnosed worldwide, and accounts for 8% of all cancer deaths

9/05/2023

Colon and Rectal Cancer Pharmacology Review


Epidemiology: Fourth most common type of cancer, estimated new cases in 2022: 151,030, Median age at diagnosis: 66 years...

2/05/2023

Surgical Management of Recurrent Rectal Cancer


Many changes have occurred in the management of rectal cancer in the last several decades. These changes have included transition of radiation and chemotherapy to the neoadjuvant setting, new and improved chemotherapy regimens, and focus on high quality surgery with total mesorectal excision. Together, this change in strategy has resulted in a dramatic decrease in local recurrence rates from 20% down to approximately 10%.

25/04/2023

Young-Onset Colorectal Cancer: Current State of Knowledge and Future Perspectives


Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related mortality worldwide

24/04/2023

Rectal Cancer: Local Excision


Local excision for a rectal tumor dates back to the early 1800s, with a report by Dr. Jacques Lisfranc describing excision of a benign rectal mass in the lower rectum.

18/04/2023

The Role of Transanal Total Mesorectal Excision (TaTME) in the Surgical Management of Rectal Cancer


The oncologic principle of total mesorectal excision (TME), introduced by Heald and colleagues,[1] involves dissection along the mesorectal fascial plane and removing the rectum and mesorectum as one intact specimen. TME is associated with decreased local recurrence and improved cancer-free survival rates and remains the gold standard surgical technique for rectal cancer. Laparoscopic TME has since been demonstrated to have better short-term and long-term surgical outcomes with no significant oncologic differences in local recurrence and disease-free survival in comparison to the open approach

17/04/2023

Surgical Management of Patients with Rectal Cancer: LAR/APR


Management of rectal cancer requires a multidisciplinary approach, which includes: oncology, pathology, radiation oncology, radiology, genetics, ostomy consultation and colorectal surgery

11/04/2023

Workup and Evaluation of Patients with Rectal Cancer


Rectal cancer is among the most common malignancies, making up 9.4% of all new cancer diagnoses with an estimated worldwide incidence of over 700,000 cases in 2020

10/04/2023

Neuroendocrine Tumors of the Colon and Rectum


Neuroendocrine tumors (NETs) of the colon and rectum are a rare malignancy. NETs represent about 1% of colonic malignancies and about 2% of rectal malignancies

1/04/2023

Neuroendocrine Tumors of the Appendix


Neuroendocrine tumors (NET) are the most commonly diagnosed neoplasms of the appendix, comprising approximately 50% of all appendiceal cancers

7/03/2023

Colon cancer: diagnosis, treatment, and emerging frontiers


Colorectal cancer (CRC) is currently the third leading cause of cancer-related deaths, among men and women, in the United States. 104,610 new cases of colon cancer are expected in the United States in the year 2020

3/10/2022

Surgical Management of Peritoneal Metastases from Colorectal Cancer


The peritoneal cavity is the third most common metastatic site for colorectal cancer (CRC) after the liver and lungs. Approximately 8-13% of CRC patients have synchronous or metachronous peritoneal metastases, with up to 2/3 occurring at the moment of diagnosis

2/10/2022